Defensive end Aaron Donald stands as the sole player on the Los Angeles Rams’ Week 1 injury report ruled out for the 2026 regular season opener against the San Francisco 49ers at Melbourne Cricket Ground. The remainder of the Rams’ listed players were estimated as full participants during Thursday’s practice and carry no injury designations for the contest, which kicks off at 5:35 p.m. Pacific Time Thursday (10:35 a.m. Australian Eastern Standard Time Friday) on Netflix.
Rams Injury Report: Donald Out, Garrett Cleared
Donald’s absence comes as no surprise. Head coach Sean McVay had already ruled out the perennial All-Pro before the team departed Los Angeles for Melbourne. Meanwhile, outside linebacker Myles Garrett received a clean bill of health, with McVay stating he would be “ready to go” for the season opener.
Every other Rams player listed on the injury report practiced fully on Thursday and holds no designation, signaling full availability for the historic international matchup.
49ers Injury Report: Bosa and Kittle Cleared, Collins Out
San Francisco enters the game with its key stars available. Defensive end Nick Bosa (knee) and tight end George Kittle (Achilles) carry no injury designations, indicating both are good to go.
However, the 49ers will be without defensive tackle Alfred Collins, who has been ruled out with a knee injury. Defensive tackle James Thompson (hamstring) is listed as questionable, leaving his status uncertain for Friday’s kickoff in Melbourne.
Final Injury Designations
Los Angeles Rams
- Out: Aaron Donald (DE)
- No Designation (Full Participant*): Myles Garrett (OLB) and all other listed players
San Francisco 49ers
- Out: Alfred Collins (DT, knee)
- Questionable: James Thompson (DT, hamstring)
- No Designation: Nick Bosa (DE, knee), George Kittle (TE, Achilles)
NIR = Not Injury Related; * = practice report is an estimation.

